Valeroyl Salicylate is a non-steroidal anti-inflammatory agent and can lead to extension of lifespan, delays age-dependent decline of locomotor activity, and increases stress resistance.

Memantine, an amantadine derivative with some dopaminergic effects, has been proposed as an antiparkinson agent and has may be used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors.

IRS1 - derived peptide